Ultrasonic atomization and subsequent polymer desolvation for peptide and protein microencapsulation into biodegradable polyesters
نویسندگان
چکیده
منابع مشابه
Biomedical Applications of Biodegradable Polyesters
The focus in the field of biomedical engineering has shifted in recent years to biodegradable polymers and, in particular, polyesters. Dozens of polyester-based medical devices are commercially available, and every year more are introduced to the market. The mechanical performance and wide range of biodegradation properties of this class of polymers allow for high degrees of selectivity for tar...
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A novel series of peptide based hybrid polymers designed to undergo enzymatic degradation is presented, via macrosubstitution of a polyphosphazene backbone with the tetrapeptide Gly-Phe-Leu-Gly. Further co-substitution of the hybrid polymers with hydrophilic polyalkylene oxide Jeffamine M-1000 leads to water soluble and biodegradable hybrid polymers. Detailed degradation studies, via 31P NMR sp...
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Drug delivery has become increasingly important mainly due to the awareness of the difficulties associated with a variety of old and new drugs. Of the many polymeric drug delivery systems, biodegradable polymers have been used widely as drug delivery systems because of their biocompatibility and biodegradability. The majority of biodegradable polymers have been used in the form of microparticle...
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Molecular farming technology offers a unique advantage that almost any protein can be produced economically and safely under very controlled conditions. Besides traditional production systems, such as bacteria, yeasts, insects and mammal cell lines, plants can now be used to produce eukaryotic recombinant proteins, especially therapeutic ones. Their advantages as hosts for protein production in...
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Single crystals of biodegradable aliphatic polyesters, poly([R]-3-hydroxybutyrate), poly([R]-3-hydroxyvalerate), poly(L-lactic acid), poly( -propiolactone), poly(4-hydroxybutyrate), poly(Æ-valerolactone), poly("caprolactone), poly(ethylene succinate) and poly(tetramethylene adipate), were grown from dilute solution by isothermal crystallization, and the crystal structures and morphologies were ...
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ژورنال
عنوان ژورنال: Journal of Microencapsulation
سال: 2003
ISSN: 0265-2048,1464-5246
DOI: 10.1080/0265204031000148059